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Custom nucleic acid solutions
Location： Home - Service Center - Service

  • Expertise & Platform: Leveraging years of nucleic acid chemistry expertise, we have built a comprehensive platform covering the entire oligonucleotide drug R&D chain for custom raw materials.

  • Product Portfolio: We offer a full range of raw materials from monomers to complex conjugates, including phosphoramidites, nucleosides, GalNAc conjugates, succinates, phosphorus reagents, and enzymatic synthesis components.

  • Applications & Support: Our products support ASO, siRNA, miRNA, aptamers, and other oligonucleotide drugs from early discovery and process development through to commercial production.

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Core Raw Material Categories

We offer comprehensive raw materials for oligonucleotide drug development, including standard and modified phosphoramidites (2′-F, 2′-OMe, 2′-MOE, LNA, ENA, with custom base/fluorescent modifications), natural and modified nucleosides, multi-arm GalNAc conjugates with various linkers, succinates and solid supports (CPG/polymer), phosphorus reagents (phosphitylating, phosphorylating, oxidizing agents), and enzymatic synthesis substrates/enzymes, covering all stages from sequence assembly to delivery modification.

Chemical Synthesis Capabilities

Our full-scale synthesis system ranges from milligram to kilogram, following QbD principles with rigorous process control and intermediate testing. With multiple patents, we stably supply GalNAc series, modified nucleosides, phosphoramidites, and functional linkers, demonstrating verified batch-to-batch consistency to support early-stage R&D through commercial production.

Custom Service Models

Our flexible service addresses diverse needs including special modifications, purity specifications, packaging, and delivery timelines. Dedicated teams evaluate synthetic routes and scale from lab to pilot. For long-term or exploratory projects, FTE-based collaboration opens access to expert resources and full facilities. Project-based management ensures seamless R&D-to-production transition, accelerating the journey from sequence to clinical development.

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